Ralph’s gift – the Ralph Ernst PhD Scholarship in Prostate Cancer Research
Sam Rollin, recipient of the inaugural Ralph Ernst PhD Scholarship in Prostate Cancer Research, says Ralph and Pixie’s generosity is providing him with the opportunity to make an incredible difference.
“I’m so grateful to Ralph and Pixie for the chance to work with Associate Professor Luke Selth and his team because it’s allowing me to play my part researching this devastating disease so we can improve outcomes for patients facing the poorest prognoses,” says Sam.
Under Associate Professor Selth’s leadership (pictured left), the team are focused on understanding how prostate cancer becomes resistant to Androgen Deprivation Therapy – the current frontline hormone therapy treatment for men with metastatic prostate cancer.
“Most patients get some benefit from this treatment, but the side effects can be nasty,” Associate Professor Selth explains.
“Unfortunately, once tumours become resistant to this therapy, the cancer is incurable and can rapidly progress.
“If we want to eventually cure men with metastatic prostate cancer, then the current therapies aren’t going to do it, so our work is really focused on developing new therapies with fewer side effects.”
One of these therapies focuses on manipulating the androgen receptor – the major driver of prostate cancer cell growth – to potentially make prostate tumours more sensitive to immunotherapy treatment.
For more information about this research, click here.
Other stories from our Spring 2021 Newsletter
Thanks to generous supporters of eye health at Flinders, researchers are hoping to improve the lives of children with glaucoma by identifying genes which lead to more severe outcomes, while also focusing on methods to improve quality of life for patients, and their families. Read More
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